Stress granules are clusters of proteins that assemble inside cells exposed to stressful conditions, such as lack of oxygen, toxic agents or infections, and enable the cell to survive.

Although the dynamic nature of germ cell granules is not well defined, they are also thought to store maternal mRNAs. In stressed cells, sequestration of mRNA in granules might contribute to ...

Therefore, the team developed a groundbreaking droplet extraction method to isolate these granules directly from cells and analyze their content. Surprisingly, the team found that the DHX9 ...

The immune system’s natural killer (NK) cells are large granular cells that constitute the third major lymphocyte subset, representing around 10-15% of circulating lymphocytes in the blood.

Stress granules (SGs) are transient organelles that form when cells experience stress, serving as critical hubs for RNA metabolism and cellular survival.

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...