To become infectious, HIV has to undergo a maturation process, which involves a rearrangement of the matrix proteins (red).

Supercomputer simulations have revealed how changes in the shape of the HIV-1 capsid protein may help the virus squeeze its inner core into the host cell's nuclear membrane. The findings, by a ...

Protein crystallization at the SER-CAT beamline at Argonne’s Advanced Photon Source proved key to the discovery of a new HIV vaccine candidate.

What about viruses? Would you consider them living or nonliving? Let’s look closely at the life cycle of the human immunodeficiency virus (HIV) – the virus that causes AIDS – to find out. This ...

They graphically represent the life cycle of HIV-1, from the initial binding of the viral particle onto a host cell (Viral Entry), through insinuation into the host cell's nucleus to spark the ...

Human immunodeficiency virus type 1 (HIV-1 ... provide a potential explanation for the evolution of the unique HIV capsid structure: its conical shape might be necessary to break the nuclear ...

In an interview with the AP, UNAIDS Executive Director Winnie Byanyima called on the Trump Administration not to cut off ...

The human immune deficiency virus (HIV) first entered public consciousness ... and they form a new structure," said Chelico. "APOBEC proteins are part of a natural defense system against viruses ...

Figure 1: Structural organization of Gag-Pol polyprotein in HIV-1. We speculated that the ... for the regulation of protease activity in the virus replication cycle. Figure 2: Protease precursor ...