Obesity is a global health concern closely linked to a range of metabolic diseases, such as type 2 diabetes and ...

We describe a model of energy homeostasis to better understand neuronal pathways that control energy balance and their regulation by hormonal signals such as insulin and leptin. Catabolic neuronal ...

Additionally, all components of the TGF-β Dauer signaling pathway are required for the ... role of TGF-β in systemically ...

Obesity is a global health concern closely linked to a range of metabolic diseases, such as type 2 diabetes and ...

This important study provides solid evidence that glucosylceramide synthase (GlcT), a rate-limiting enzyme for glycosphingolipid (GSL) production, plays a role in the differentiation of intestinal ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

promoting homeostasis with neither unregulated growth nor inappropriate cell loss. However, the real cellular world is laden with oncogenes and tumor suppressor genes whose products interact in ...

A transformative study has uncovered the pivotal role of the protein Naked cuticle homolog 2 (NKD2) in regulating the differentiation of bone-forming osteoblasts and bone-resorbing osteoclasts.

Human adults do not have significant amounts of BAT, so the team looked at human skeletal muscle—vital for energy homeostasis in humans. In both human muscle cells and mouse brown adipocytes ...