We are driven to understand the signals regulating tissue-specific autophagy signalling in mammalian health and disease. Understanding the physiological regulation and significance of selective ...

Atherosclerosis (AS) is a chronic inflammatory disease characterized by the buildup of lipids and immune cells in arterial ...

Caption Cellular homeostasis depends on the timely clearance of damaged cellular organelles and proteins via pathways including autophagy. Mitochondria and mitochondrial autophagy play a vital ...

A Japanese research team found that the oxidized form of glutathione (GSSG) may protect heart tissue by modifying a key ...

MOTS-c, a mitochondrial-derived peptide, has garnered scientific interest due to its hypothesized role in cellular metabolism ...

Metabolic-dysfunction-associated steatotic liver disease (MASLD) arises from excessive intrahepatic triglyceride accumulation ...

Prof. Shan Tizhong's team at Zhejiang University discovered that lard derived from subcutaneous adipose tissue (SAT), as a ...

E2-based therapeutics show early promise in addressing neurological disorders and oncology applications. BPGbio's protein homeostasis program includes 1,000+ proprietary Ro3 fragments, which ...