Prince Frederik was battling a rare genetic condition called POLG Mitochondrial disease, which left him barely able to speak ...
He was 22. Frederik died from a rare genetic condition called POLG Mitochondrial disease, his dad announced in a statement shared on the POLG Foundation website. “It is with a very heavy heart ...
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Targeting mitochondrial DNA integrity for cardiac protection after injuryMaintaining mitochondrial DNA (mtDNA) integrity is crucial for cardiomyocyte function, and its disruption plays a significant role in ischemia/reperfusion (I/R) injury.
PolG disease is a mitochondrial disorder caused by mutations in the POLG gene. It primarily affects multiple organs, including the brain, nerves, muscles and liver, and can affect vision.
a group of disorders caused by mutations in the POLG gene. The disease is incurable, and causes organ failure over time. Prince Frederik was diagnosed at the age of 14 and his health had ...
Polymerase gamma becomes a mutator polymerase ... Even as mutator polymerases inactivated one gene after another, plenty of undamaged mitochondria would remain to permit normal cellular function.
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