All critical biological processes are regulated through interactions between proteins. However, regulatory interactions can also involve small molecules that can result in unique changes to ...

The availability of large-scale protein-protein interaction data has led to the recent popularity of the study of protein interaction networks. Just as the enormous amount of available sequence ...

Now, researchers from Japan have reported a newly discovered protein interaction that regulates sperm development. In a study published in PNAS, a multi-institutional research team led by Osaka ...

The identification of protein interactions has been greatly simplified by the invention of yeast-based screening assays such as the yeast two-hybrid system. However, yeast two-hybrid assays cannot ...

Protein-protein interactions facilitate everything from transcribing DNA and controlling cell division to higher-level functions in complex organisms. Much remains unclear, however, about how ...

In experiments conducted at the University of São Paulo, tumor stem cells became less able to proliferate and invade tissues ...

BioAFM instruments are designed to measure soft, fragile, and complex samples, including single molecules, nucleic acids, ...

To uncover the sites of protein-DNA interactions at genome scale, Bing Ren, a former postdoctoral researcher in Young’s lab and now a gene regulation researcher at the University of California, San ...

and then probed with labeled antibodies or other ligands to detect specific protein-protein interactions or post-translational modifications. Proteomics plays a crucial role in the discovery of ...

Researchers found that TEX38 and ZDHHC19 co-localize on the plasma membrane of spermatids and mediate S-palmitoylation of ARRDC5, a crucial protein for spermatogenesis. Disrupting either TEX38 or ...