This regulation keeps glycolysis, the process by which cells convert glucose into energy, in Purkinje cells low, thereby ...

Cerebellar rhythm loss due to climbing fiber regression is a shared pathophysiology of motor deficits across cerebellar ...

In principle, this can be assessed by measuring the distinctive firing patterns, known as complex spikes, generated by Purkinje cells — the neurons that generate the output of the cerebellum.

The normal conduction system in the ventricles is called the His-Purkinje system and consists of cells that can conduct electricity quite rapidly. Thus, normal conduction of an electrical impulse ...

In this case, we combine electrophysiology, multi-photon imaging, and biophysical modeling to understand the computational function of changes in intrinsic excitability in cerebellar Purkinje cells.