A new method for mapping torsion provides insights into the ways that the genome responds to the torsion generated by RNA polymerase II.

Ring-shaped extrachromosomal DNA is implicated in many cancers. Rachel Brazil talks to the scientists trying to uncover their ...

Ultraviolet (UV) radiation is known to cause DNA damage, and while that damage may accumulate and eventually lead to diseases ...

The central dogma of molecular biology suggests that the primary role of RNA is to convert the information stored in DNA into proteins ... complex can then inhibit transcription of an mRNA ...

Understanding the process of replication and transcription of mtDNA ... in the journal Communications Biology. "While mtDNA is much smaller than nuclear DNA, it plays a crucial role in life ...

Scientists have captured the first detailed 'molecular movie' showing DNA being unzipped at the atomic level -- revealing how cells begin the crucial process of copying their genetic material.

Sunburns and aging skin are obvious effects of exposure to harmful UV rays, tobacco smoke and other carcinogens. But the effects aren't just skin deep. Inside the body, DNA is literally being torn ...

For natural cells, the so-called central dogma of molecular biology describes how protein synthesis occurs through ...

Often they indicate sequence-specific binding sites for proteins such as nucleases and transcription ... tools for computational biology in the post-genomic era. Other DNA binding proteins tend ...

It was actually a really amazing application at the time to be able to measure transcription factor binding across the genome. They found that hsp70 DNA of heat-shocked cells migrated faster in a gel ...