A vast search of natural diversity has led scientists at MIT's McGovern Institute and the Broad Institute of MIT and Harvard ...

With the new nanotechnology, RNA drugs hitch a ride ... But also the possibility of curing very rare diseases with the help of gene editing." "I am very proud of this publication," concludes ...

Researchers developed a new gene-editing strategy that dramatically boosts the effectiveness of gene therapies in the liver, a breakthrough that could lead to new treatments for about 700 genetic ...

Nov. 12, 2024 — Researchers have combined two gene editing methods. This enables them to quickly investigate the significance of many genetic mutations involved in the development and treatment of ...

Gene editing is the process of adding ... and doxorubicin (Doxil). In the future, nanotechnology could be used to detect cancer early and improve outcomes. Other cancer treatments that use ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro proof-of-concept study.

Despite its advantages, TALEN also faces some challenges. The construction of TALEN proteins can be time-consuming and labor-intensive compared to other gene editing tools like CRISPR-Cas9.

When targeting the PCSK9 gene in mouse liver in vivo, NanoCas showed saturating editing efficiencies of approximately 60%, on par with that of SaCas9, which is about three-fold larger in size.