Affected populations: POLG-related diseases are a group of rare, incurable conditions caused by inherited gene mutations. These disease-causing mutations are carried by up to 2% of people of ...

PolG disease is a genetic disease caused by mutations that occur in the POLG gene in the mitochondria of a person's cell, according to the UMDF. It's one of the most commonly inherited ...

dies of rare POLG disease at 22 PolG disease is a genetic disease caused by mutations that occur in the POLG gene in the mitochondria of a person's cell, according to the UMDF. It's one of the most ...

Prince Frederik of Luxembourg died from a genetic disease called PolG, but experts hope his passing could bring more awareness to the rare condition that impacted his life. Prince Frederik, 22 ...

Mitochondria contain their own DNA which requires a specific enzyme to replicate, found in host cell’s POLG and POLG2 genes. Mutations in these genes therefore impact the ability for ...

Prince Frederik, the second cousin of the heir to the Luxembourg throne, discovered at age 14 that he had a mutation in his POLG gene, which is involved in the replication and repair of DNA.

It is named for the POLG gene, and there are more than 200 POLG mutations that can cause the disease. The POLG Foundation described the disorder as robbing cells of energy and comparing it to a ...

Prince Frederik of Luxembourg passed away from a rare mitochondrial condition affecting two of his POLG genes that he had been diagnosed with at the age of 14. His father, Prince Robert of ...

It is caused by mutations in the POLG gene that impede mitochondrial DNA’s ability to replicate correctly and deliver energy to cells. The result is “progressive multiple organ dysfunction and ...