Affected populations: POLG-related diseases are a group of rare, incurable conditions caused by inherited gene mutations. These disease-causing mutations are carried by up to 2% of people of ...

Prince Frederik of Luxembourg died from a genetic disease called PolG, but experts hope his passing could bring more awareness to the rare condition that impacted his life.

PolG disease is a genetic disease caused by mutations that occur in the POLG gene in the mitochondria of a person's cell, according to the UMDF. It's one of the most commonly inherited ...

dies of rare POLG disease at 22 PolG disease is a genetic disease caused by mutations that occur in the POLG gene in the mitochondria of a person's cell, according to the UMDF. It's one of the ...

It prevents the body’s cells to produce adequate energy, which causes multiple organ dysfunctions and failures ...

Prince Frederik, the second cousin of the heir to the Luxembourg throne, discovered at age 14 that he had a mutation in his POLG gene, which is involved in the replication and repair of DNA.

Prince Frederik of Luxembourg has died at the age of 22 due to Polymerase Gamma (PolG) mitochondrial disease, a rare genetic disorder affecting multiple organs.

PolG disease is genetic condition that depletes the body ... found in host cell’s POLG and POLG2 genes. Mutations in these genes therefore impact the ability for mitochondria to replicate.