POLG-related diseases disrupt the function of the mitochondria, or "powerhouses" of the cell — starving them of energy.

DNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...

Studies have identified that key proteins such as transcription factor A, mitochondrial (TFAM) and DNA polymerase gamma (POLG), both critical for mtDNA maintenance, are downregulated in I/R injury.

If DNA is a book, then how is it read? Learn more about the DNA transcription process, where DNA is converted to RNA, a more portable set of instructions for the cell. The process of transcription ...