Stress granules are clusters of proteins that assemble inside cells exposed to stressful conditions, such as lack of oxygen, toxic agents or infections, and enable the cell to survive.

Although the dynamic nature of germ cell granules is not well defined, they are also thought to store maternal mRNAs. In stressed cells, sequestration of mRNA in granules might contribute to ...

Using an unbiased approach, this important study discovered a role of Ezh2 in the differentiation of granule neuron precursors, the cell of origin for Shh group of medulloblastoma. Furthermore, the ...