A new vector system known as lentiviral vectors can permanently integrate the gene into dividing and non-dividing cells. The capacity of lentiviral vectors to reliably integrate at various genomic ...

also published in The New England Journal of Medicine. Concerns are raised regarding integration of lentivirus into the host genome. Previous studies have linked lentiviral vectors to blood cancer ...

Initially, T cell engineering depended on lentiviral or retroviral vectors to deliver DNA fragments into a cell for homologous recombination. Viral vectors allow for stable integration of DNA ...

Here we report a case of a T-cell lymphoma harboring a lentiviral integration in a known tumor ... CAR was detected in high abundance in DNA extracted from the patient’s duodenal-biopsy samples ...

We provide transgene expression in mammalian cell lines using lentiviral and retroviral transduction and ... editing in different mammalian cell lines for research purposes. Genome editing by ...

The clones are available as glycerol stocks, plates, DNA minipreps or midipreps ... The constructs are in pLKO.1 lentiviral vector with puromycin selection. Carbenicillin selection is used for the ...