This valuable work presents how PRDM16 plays a critical role during colloid plexus development, through regulating BMP signaling. Solid evidence supports the context-dependent gene regulatory ...

Cancer is a perennial fear for therapies that involve altering DNA in cells ... said the latest analysis showed that the integration site of the vector was in a gene called VAMP4.

Recombinase efficiency increases allow Qi Biodesign to insert 20-30 kb (5 or 6 genes) at one time at one location across a variety of different crop genetics. In addition, a large team at Qi Biodesign ...

In the last several years, large language models (LLMs) like ChatGPT and Bard have shown the world the astounding power of ...

Monoclonal T cells from both patients had detectable CAR transgene expression and integration ... T-cell therapy that is produced by means of lentiviral transduction. In the phase 3, randomized ...

Researchers trial inhalable gene therapy for cystic fibrosis, offering a potential breakthrough in treating the genetic lung ...

These useful findings assigned a novel functional implication of histone acylation, crotonylation. Although the mechanistic insights have been provided in great detail regarding the role of the YEATS2 ...

Large consortia-led projects such as ENCODE (Encyclopedia of DNA Elements) have made great strides in identifying various functional elements of the genome. These include enhancers, activators, and ...

This method of bacterial genome sequencing could be used to identify antibiotic-resistant strains—for example, in patients with urinary tract infections—or to locate beneficial strains in fecal ...

detection methods using whole genome sequencing data are affected by the measurement scale and parameters, and the breakpoint of CNVs is easily influenced by the sizes of windows in preparing RD ...