DNA segments that can move from one part of the genome to another—are key to bacterial evolution and the development of ...

Tuberculosis remains one of the most lethal infectious diseases caused by a single pathogen. According to the latest global ...

The Global Viral Vector Market was valued at approximately USD 3.10 billion in 2022 and is projected to grow at a robust CAGR of more than 11.5% during the forecast period 2023-2030. Read the Market ...

This study provides evidence that single-cell multi-omics profiling can reveal key regulators of HIV-1 persistence and early immune dysregulation, particularly implicating KLF2 and Th17 cells as major ...

Genome informatics is the field in which computer and statistical techniques are applied to derive biological information from genome sequences. Genome informatics includes methods to analyse DNA ...

under the Genome India Project (GIP). The sequences of healthy individuals — from 99 ethnic populations of the country — have helped create a baseline map of India’s genetic diversity. This dataset is ...

Currently, WGS, Cas9 ChIP–seq (chromatin immunoprecipitation followed by high-throughput sequencing), IDLVs (integrase defective lentiviral vectors), GUIDE–seq (genome-wide, unbiased identification of ...

X-linked sideroblastic anemia (XLSA) is a rare genetic disorder caused by mutations in the ALAS2 gene, which plays a critical role in heme biosynthesis within red blood cells.

The comprehensive data set includes: High-Quality Whole Genome Sequencing Data: Providing insights into genetic variations that may influence drug efficacy, metabolism, and safety. Longitudinal ...

Crucially, it usually requires only a single injection, whether that be a gene replacement strategy for an inherited disorder or the delivery of a genome- or epigenome ... human immunodeficiency virus ...

These results indicated that expression of specific HSV proteins can be reduced by targeting the viral genes encoding the corresponding proteins using sequence-specific single or double sgRNAs. These ...