comprehensive map of all the genes essential for blood infections in Plasmodium knowlesi (P. knowlesi), a parasite that causes malaria in humans, has been generated. The map contains the most ...

Malaria was believed to be caused by miasma ... s life cycle by inducing an immune response against the circum-sporozoite protein (CSP) found on Plasmodium sporozoites. This stage infects the ...

Figure Malaria vaccination timeline: key milestones and events in the WHO African Region in 2024 Despite these achievements, several challenges posed notable threats to the sustainability and ...

shows the dynamics of 3D11 anti-CSP monoclonal antibody (mAb) mediated elimination of rodent malaria Plasmodium berghei (Pb) parasites in the liver. The authors show that the anti-CSP mAb could ...

the causative agent of malaria, target the asexual blood stages ... First, for all parasite species, the low efficiency of sporozoite invasion and maturation in cultured primary hepatocytes ...

Most recommendations in this chapter fall into the category of "good practice", in the sense that there is no reasonable alternative (e.g. testing for malaria should be done in a febrile traveller ...

Malaria is one of the most devastating diseases across the globe, particularly in low-income countries in Sub-Saharan Africa. The increasing incidence of malaria morbidity is mainly due to the ...

Malaria remains at the forefront of scientific research and global political and funding agendas. Malaria models have consistently oversimplified how mass interventions are implemented. Here, we ...

We also emphasize the potential inflammatory cascade resulting from Plasmodium life cycle progression after sporozoite inoculation and ultimately culminating in cerebral malaria pathology (Figure 1).