Two weeks after Prince Frederik of Luxembourg died from POLG, a documentary filmmaker has revealed that the 22-year-old struggled to "get up by himself" as he battled the rare genetic disorder in an ...

This gene encodes a protein in mitochondria, called DNA polymerase gamma (pol γ), which is needed to replicate ... POLG mutations are the most common cause of inherited mitochondrial disorders, with ...

In people with POLG-related diseases, issues with polymerase gamma can either end up decreasing the amount of DNA in mitochondria ... common cause of inherited mitochondrial disorders, with ...

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Estimates vary, but roughly one in 10,000 people are thought to have POLG, or polymerase gamma disease, according to the United Mitochondrial ... organisation used his DNA for research, initiated ...

When the POLG gene — responsible for mitochondrial DNA replication — is mutated, the mitochondria fail to produce enough energy to sustain critical bodily functions, affecting the brain, nerves, ...

These mutations "compromise the functioning of the enzyme responsible for mitochondrial DNA maintenance." Symptoms differ depending on when the disease first emerges. For those with disease onset ...

Estimates vary, but roughly one in 10,000 people are thought to have POLG, or polymerase gamma, disease, according to the United Mitochondrial ... organization used his DNA for research, initiated ...

Prince Frederik of Luxembourg, son of Prince Robert of Luxembourg and Princess Julie of Nassau, has died at the age of 22 due to a rare genetic disorder known as PolG mitochondrial disease.

The small study in patients with a rare disorder that causes liver and lung damage showed the potential for precisely targeted infusions. By Gina Kolata Researchers have corrected a disease ...

Prince Frederik died on March 1 from POLG Mitochondrial disease, his father announced in a lengthy statement on The POLG Foundation’s website. POLG Mitochondrial disease is a genetic disorder that ...