A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

Japanese researchers used a nonviral piggyBac system to genetically modify cynomolgus monkeys, enabling more accurate disease ...

ADHD likely has a genetic component. If a biological parent or sibling has ADHD, you’re more likely to have it, too, but this doesn’t mean you will. Your environment can be influential as well.

POLG-related diseases disrupt the function of the mitochondria, or "powerhouses" of the cell — starving them of energy.

The son of Prince Robert of Luxembourg and Princess Julie of Nassau, Prince Frederik, has died in Paris the age of 22 due to ...

POLG mitochondrial disease is a rare genetic disorder caused by mutations in the POLG gene, which plays a critical role in mitochondrial function. Mitochondria are responsible for generating energy in ...

It is a hereditary disorder caused by mutations in the POLG gene, which encodes an enzyme essential for mitochondrial DNA replication. In the case of Prince Federico, the disease manifested at the age ...

Mitochondria contain their own DNA which requires a specific enzyme to replicate, found in host cell’s POLG and POLG2 genes. Mutations in these genes therefore impact the ability for ...

A mitochondrial condition known as POLG disease is caused by hereditary mutations in the POLG gene, which is essential for DNA repair and cell genetic material replication. Numerous organs ...

encoded in the host cell’s POLG and POLG2 genes. Mutations in those genes impair efficient replication of the mitochondria DNA. POLG symptoms, which can be mild to severe, most often include ...

which relies on an enzyme called polymerase γ (“POLG”)—encoded by the POLG and POLG2 genes in the host cell for replication. Mutations in these genes disrupt mitochondrial DNA replication ...