Australian researchers are providing new hope for a cruel killer disease with royal connections. Called mitochondrial disease ...

POLG-related diseases disrupt the function of the mitochondria, or "powerhouses" of the cell — starving them of energy.

His work through The POLG Foundation continues to inspire efforts toward finding a cure. POLG mitochondrial disease is a rare genetic disorder caused by mutations in the POLG gene, which plays a ...

But, what exactly is the POLG mitochondrial disease and why is it so difficult to diagnose? It is a hereditary disorder caused by mutations in the POLG gene, which encodes an enzyme essential for ...

Mitochondria contain their own DNA which requires a specific enzyme to replicate, found in host cell’s POLG and POLG2 genes. Mutations in these genes therefore impact the ability for ...

It prevents the body’s cells to produce adequate energy, which causes multiple organ dysfunctions and failures ...

A mitochondrial condition known as POLG disease is caused by hereditary mutations in the POLG gene, which is essential for DNA repair and cell genetic material replication. Numerous organs ...

encoded in the host cell’s POLG and POLG2 genes. Mutations in those genes impair efficient replication of the mitochondria DNA. POLG symptoms, which can be mild to severe, most often include ...

Prince Frederik of Luxembourg, aged 22, passed away from POLG mitochondrial disease, a rare genetic disorder. His father announced the news and praised Frederik's courage and dedication to raising ...

POLG disease is a mitochondrial disorder caused by mutations in the POLG gene. It typically affects multiple organs, primarily the brain, nerves, muscles, and liver, and can affect vision due to ...

PolG disease is a genetic disease caused by mutations that occur in the POLG gene in the mitochondria of a person's cell, according to the UMDF. It's one of the most commonly inherited ...