Discover effective strategies to minimize sickle cell pain crises and avoid hospitalizations. Leading hematologists share ...

When Vijay Sankaran was an MD-PhD student at Harvard Medical School in the mid-2000s, one of his first clinical encounters ...

Sickle cell disease is a genetic blood disorder characterised by the production of abnormal haemoglobin, which causes red blood cells to become rigid and sickle-shaped. These cells tend to clump ...

Novo Nordisk's rare disease unit awaits Phase 3 data for etavopivat in sickle cell disease, aiming for 50% VOC reduction ...

Pfizer is voluntarily withdrawing its sickle cell disease (SCD) therapy Oxbryta from all world markets after finding an "imbalance" in deaths in its clinical trials programme. It's a blow to the ...

Undergoing a bone marrow transplant during adolescence, but not in adulthood, may lower the risk of stroke with SCD, a mouse ...

9 1. Sickle cell disease. National Organization for Rare Disorders (NORD). Accessed November 28, 2021. 2. Sickle cell disease. National Heart, Lung, and Blood Institute. Updated September 1, 2020.

Over the last few months, there have been multiple reports on new treatments for sickle cell disease. In this feature, we highlight the biggest updates in this field and think about what the future ...

June 10, 2024 — Scientists have grown 'mini-guts' in the lab to help understand Crohn's disease, showing that 'switches' that modify DNA in gut cells play an ... Major Cause of Inflammatory ...

2024 — Stem cell transplantation is used to treat several types of blood cancers, but carries the risk of a life-threatening side effect called graft-versus-host disease. Results from a clinical ...

Sickle cell disease is a life-threatening inherited blood disorder affecting more than 100 000 Americans and millions ...

It is well-established that patients with sickle cell disease (SCD) are at substantial risk of neurological complications, including overt and silent stroke, microstructural injury, and cognitive ...