Mar 2, 2025 · Aging ischemic strokes can be important in a number of clinical and medicolegal settings. Both CT and MRI can help in determining when a stroke occurred as imaging features evolve in a reasonably predictable fashion. There is substantial heterogeneity in the terminology denoting time from onset.

Jun 30, 2008 · MCA infarction: on CT an area of hypoattenuation appearing within six hours is highly specific for irreversible ischemic brain damage. The reason we see ischemia on CT is that in ischemia cytotoxic edema develops as a result of failure of the ion-pumps. These fail due to an inadequate supply of ATP.

Mar 4, 2024 · The key to interpreting CT perfusion in the setting of acute ischemic stroke is understanding and identifying the infarct core and the ischemic penumbra, as a patient with a small core and a large penumbra is most likely to benefit from reperfusion therapies. The three parameters typically used in determining these two areas are:

With modern CT imaging a comprehensive overview of cerebral macro- and microcirculation can be obtained within minutes in acute ischemic stroke. This opens for patient stratification and individualized treatment.

Non-contrast brain computed tomography (NCCT) remains the most common imaging modality employed to select patients for thrombolytic therapy in acute ischemic stroke. The current study used the Alberta Stroke Program Early CT Score (ASPECTS) to ...

Initial stroke imaging can be done using either noncontrast head CT or MRI to differentiate hemorrhagic (15%) from ischemic stroke and determine the size (whether it is more than one-third of the middle cerebral artery [MCA] territory) and location.

Mar 2, 2025 · Terminology. The term "stroke" is a clinical determination, whereas "infarction" is fundamentally a pathologic term 1.. Bridging these terms, ischaemic stroke is the subtype of stroke that requires both a clinical neurologic deficit and evidence of CNS infarction (cell death attributable to ischaemia). The evidence of infarction may be based on imaging, pathology, and/or persistent neurologic ...

Sep 24, 2009 · Potential utility for perfusion imaging in acute stroke includes the following: (1) Identification of brain regions with extremely low cerebral blood flow (CBF), which represent the core (tissue likely to be irreversibly infarcted despite reperfusion) that is at increased risk of hemorrhage with thrombolysis; (2) identification of patients with ...

Feb 9, 2023 · Current international recommendations advocate the use of noncontrast CT for the selection of patients eligible for IVT and mechanical thrombectomy within the first 4.5 and 6 hours from the stroke onset.

Mar 14, 2013 · Computed tomography (CT) remains the initial imaging modality of choice in hyperacute stroke (HIS). CT scanners are more widely available than MRI scanners and are often located in emergency departments of district hospitals. Noncontrast CT (NCCT) excludes intracranial hemorrhage and tumor and detects early signs of infarction.