Left-sided heart failure and right-sided heart failure refer to different conditions affecting the heart's ability to pump blood effectively. In left-sided heart failure, the left ventricle, which is responsible for pumping oxygenated blood to the body, becomes weak or stiff, leading to inadequate blood flow to the body's organs and tissues. This can result in symptoms such as shortness of breath, fatigue, and fluid accumulation in the lungs. On the other hand, right-sided heart failure occurs when the right ventricle, responsible for pumping deoxygenated blood to the lungs for oxygenation, is impaired. This can cause blood to back up into the veins, leading to fluid accumulation in the legs, abdomen, and other parts of the body. Symptoms of right-sided heart failure may include swelling in the legs, ankles, or abdomen, fatigue, and liver congestion. While left-sided heart failure is more common and often precedes right-sided heart failure, both conditions can occur independently or together.