Jan 7, 2025 · 1. In a cohort of adults with chronic obstructive pulmonary disease (COPD), receiving fluticasone-umeclidinium-vilanterol was not associated with improved clinical outcomes compared to receiving budesonide-glycopyrrolate-formoterol. Evidence Rating Level: 2 (Good) Treatment recommendations for chronic obstructive pulmonary disease (COPD) include triple inhaler combination therapy with an ...

Title Year Journal Citations Key findings; The UKPDS: Reducing the risk of diabetes-related morbidity and mortality: 1998: Lancet: 20,000: 1. For patients with type 2 diabetes mellitus, pharmacologic blood glucose control with sulfonylureas or insulin significantly reduces the risk of microvascular complications, but not macrovascular complications

Sep 27, 2014 · 1. The Lee index is a prospectively validated model that predicts the risk of a cardiac event in patients undergoing noncardiac surgery. 2. The six independent predictors are as follows: 1) high-risk surgery, 2) history of ischemic heart disease, 3) history of congestive heart failure, 4) history of cerebrovascular disease, 5) preoperative treatment with insulin,

Dec 3, 2023 · 1. The Child-Pugh score consists of five clinical features and is used to assess the prognosis of chronic liver disease and cirrhosis. 2. The Child-Pugh score was originally developed in 1973 to predict surgical outcomes in patients presenting with bleeding esophageal varices.

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Jun 14, 2024 · Awiqli led to greater glycated hemoglobin (HbA1c) reduction, superior blood sugar reduction, and time spent within the recommended blood sugar range compared to daily basal insulin. The rate of hypoglycemia and other adverse events were similar in the Awiqli group compared to the standard basal insulin group. The Latest Insulin icodec (Awiqli) is an

Dec 16, 2024 · 1. Symptom recovery trajectories in children aged 5 to 12 years of age suffering from sport-related concussions (SRCs) and non-sport-related concussions (non-SRCs) were similar, with no significant differences in recovery curves across time postinjury. Evidence Rating Level: 2 (Good) Study Rundown: A huge proportion of concussions in young children are associated with sports and recreational

Oct 2, 2024 · 1. In this randomized controlled trial, among patients with severe hypoxemia, long-term oxygen therapy used for 24 hours per day resulted in no reduction in risk of hospitalization or death within one year compared with oxygen therapy for 15 hours per day. 2. Oxygen therapy for 15 versus 24 hours per day was associated with

Feb 17, 2025 · Meconium-Related Obstruction and Clinical Outcomes in Term and Preterm Infants 1. Nearly 95% of cases of meconium-related obstruction (MRO) occur in the absence of cystic fibrosis or Hirschsprung disease 2. MRO occurred most frequently in preterm infants, who more often experienced longer hospital stays and required surgical intervention Evidence Rating Level: 2 (Good) Historically, the

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